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Ritonavir or lopinavir/ritonavir significantly maximize plasma concentrations of oxycodone in healthy human volunteers as a result of inhibition of CYP3A4 and CYP2D6.[58] Rifampicin greatly lessens plasma concentrations of oxycodone due to strong induction of CYP3A4.These medication are extremely powerful agony relievers. It is vital to find out al